Recombinant FOXP3 anticorps (AA 52-276)

N° du produit ABIN7795820

Cet anticorps Lapin Monoclonal détecte spécifiquement FOXP3 dans IHC. Il présente une réactivité envers Souris.

Aperçu rapide pour Recombinant FOXP3 anticorps (AA 52-276) (ABIN7795820)

Antigène: FOXP3 (Forkhead Box P3 (FOXP3))

Type d'anticorp: Recombinant Antibody

Reactivité: Souris

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp FOXP3 est non-conjugé

Application: Immunohistochemistry (IHC)

Clone: BLR374N

Détail du produit anti-FOXP3 anticorps

Épitope: AA 52-276

Fonction: Rabbit anti-FOXP3 Recombinant Monoclonal Antibody [BLR374N]

Purification: Purified

Immunogène: residues 52-276

Isotype: IgG

Information d'application

Indications d'application: IHC,1100 to 1500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1000 μg/mL

Buffer: Phosphate Buffered Saline (PBS) with 0.09 % Sodium Azide, BSA-Free

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: 2 - 8 °C

Date de péremption: 12 months

Détails sur FOXP3

Antigène: FOXP3 (Forkhead Box P3 (FOXP3))

Autre désignation: FOXP3

Sujet: FOXP3 is a transcriptional regulator which is crucial for the development and inhibitory function of regulatory T-cells (Treg). It plays an essential role in maintaining homeostasis of the immune system by allowing the acquisition of full suppressive function and stability of the Treg lineage, and by directly modulating the expansion and function of conventional T-cells. FOXP3 can act either as a transcriptional repressor or a transcriptional activator depending on its interactions with other transcription factors, histone acetylases and deacetylases.  [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q9BZS1].

ID gène: 20371

UniProt: Q99JB6

Pathways: Chromatin Binding, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Activated T Cell Proliferation